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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Cancer of the prostate presenting with diffuse osteolytic metastatic bone lesions: A case report
Journal of Medical Case Reports, Volume 6, Article 425, Year 2012
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Description
Introduction. Prostate cancer is the second most common cancer in men and the fifth most common cancer worldwide. In the USA it is more common in African-American men than in Caucasian men. Prostate cancer frequently metastasizes to bone and the lesions appear osteoblastic on radiographs. Presentation with diffuse osteolytic bone lesions is rare. We describe an unusual presentation of metastatic prostate cancer with diffuse osteolytic bone lesions. Case presentation. A 65-year-old Namibian man presented with anemia, thrombocytopenia and worsening back pains. In addition he had complaints of effort intolerance, palpitations, dysuria and mild symptoms of bladder outlet obstruction. On examination he was found to be anemic, had a swollen tender right shoulder joint and spine tenderness to percussion. On digital rectal examination he had asymmetrical enlargement of the prostate which felt nodular and hard with diffuse firmness in some parts. His prostate-specific antigen was greater than 100ng/mL and he had diffuse osteolytic lesions involving the right humerus, and all vertebral, femur and pelvic bones. His screen for multiple myeloma was negative and the prostate biopsy confirmed prostate cancer. Conclusion: Prostate cancer rarely presents with diffuse osteolytic bone lesions and should be considered in the differential diagnosis when evaluating male patients with osteolytic bone lesions. © 2012 Segamwenge et al.; licensee BioMed Central Ltd.
Authors & Co-Authors
Segamwenge, Innocent Lule
Namibia, Oshakati
Intermediate Hospital Oshakati
Mgori, N. K.
Namibia, Oshakati
Intermediate Hospital Oshakati
Abdallahyussuf, Safia
Namibia, Oshakati
Intermediate Hospital Oshakati
Mukulu, Celia
Namibia, Oshakati
Intermediate Hospital Oshakati
Nakangombe, Philip
Namibia, Oshakati
Intermediate Hospital Oshakati
Ngalyuka, Paul Kioko
Namibia, Oshakati
Intermediate Hospital Oshakati
Kidaaga, Fredrick
Namibia, Windhoek
Namibian Institute of Pathology
Statistics
Citations: 15
Authors: 7
Affiliations: 2
Identifiers
Doi:
10.1186/1752-1947-6-425
e-ISSN:
17521947
Research Areas
Cancer
Participants Gender
Male