Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

Antigen-specific interferon-gamma responses and innate cytokine balance in TB-IRIS

PLoS ONE, Volume 9, No. 11, Article e113101, Year 2014

Background: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) remains a poorly understood complication in HIV-TB patients receiving antiretroviral therapy (ART). TB-IRIS could be associated with an exaggerated immune response to TB-antigens. We compared the recovery of IFNc responses to recall and TB-antigens and explored in vitro innate cytokine production in TB-IRIS patients. Copyright:
Statistics
Citations: 11
Authors: 8
Affiliations: 6
Identifiers
Research Areas
Infectious Diseases