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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Stent-oriented versus patient-oriented outcome in patients undergoing early percutaneous coronary intervention for acute coronary syndrome: 2-year report from the BASE-ACS trial
Annals of Medicine, Volume 45, No. 7, Year 2013
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Description
Background. The BASE-ACS trial demonstrated an outcome of the titanium-nitride-oxide-coated bioactive stents (BAS) statistically non-inferior to that of the everolimus-eluting stents (EES) at 12-month follow-up in patients presenting with acute coronary syndrome (ACS). We performed a post hoc analysis of the BASEACS trial with particular focus on stent-oriented versus patientoriented outcome at 24-month follow-up. Methods. A total of 827 patients with ACS were randomly assigned to receive either BAS (417) or EES (410). Stent-oriented outcome was defi ned as a composite of cardiac death, target vessel-related non-fatal myocardial infarction, or ischemia-driven target lesion revascularization. Patient-oriented outcome was defi ned as a composite of all-cause death, any non-fatal myocardial infarction, or any revascularization. Results. Clinical follow-up for 24 months was completed in 406 (97.4%) patients in the BAS group and in 398 (97.1%) in the EES group. Stent-oriented outcome at 24-month follow-up occurred at similar frequencies in the two stent groups (10.1% for BAS versus 11.2% for EES, P = 0.53). Likewise, patient-oriented outcome at 24-month follow-up was similar in the two groups (16.3% versus 19.8%, respectively, P = 0 .2). Conclusions. In patients presenting with ACS, the rates of both stent-oriented and patient-oriented outcomes at 24-month follow-up in the BAS group were similar to those in the EES group. © 2013 Informa UK, Ltd.
Authors & Co-Authors
Nammas, Wail M.
Finland, Pori
Satakunta Central Hospital
Airaksinen, Juhani K.E.
Finland, Turku
Turun Yliopistollinen Keskussairaala
Pietilä, Mikko J.
Finland, Turku
Turun Yliopistollinen Keskussairaala
Ylitalo, Antti S.
Finland, Pori
Satakunta Central Hospital
Karjalainen, Pasi Paavo
Finland, Pori
Satakunta Central Hospital
Statistics
Citations: 20
Authors: 5
Affiliations: 6
Identifiers
Doi:
10.3109/07853890.2013.833390
ISSN:
13652060
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Randomised Control Trial
Cohort Study