Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Improved microscopical diagnosis of pulmonary tuberculosis in developing countries
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 89, No. 2, Year 1995
Notification
URL copied to clipboard!
Description
The diagnosis of pulmonary tuberculosis (TB) relies on the bacteriological examination of sputum. However, microscopy of smears made directly from sputum has a low sensitivity and there is an urgent need for improved methods. We have compared microscopy of smears made directly from sputum with microscopy after liquefaction of sputum with household bleach (NaOCl) and concentration of bacteria by centrifugation. In 3 studies performed in Ethiopia and India, the use of the NaOCl method increased the number of samples positive for acid-fast bacilli by more than 100%. The technique is appropriate for developing countries and its application would increase the efficiency of TB control programmes. As a potent disinfectant, NaOCl also has the advantage of lowering the risk of laboratory infection. © 1995 Oxford University Press.
Authors & Co-Authors
GEBRE, NEGUSSIE
Ethiopia, Addis Ababa
The Annauer Hansen Research Institute
Karlsson, Ulf
Sweden, Lund
Lunds Universitet
Jönsson, Göran
Sweden, Lund
Lunds Universitet
MacAden, Ragini S.
India, Bengaluru
St. John’s Medical College
Wolde, Alemnesh
Ethiopia, Addis Ababa
Addis Ababa Tuberculosis Demonstration and Training Centre
Aseffa, Abraham
Ethiopia, Gondar
University of Gondar
Miöner, Håkan
Ethiopia, Addis Ababa
The Annauer Hansen Research Institute
Statistics
Citations: 83
Authors: 7
Affiliations: 5
Identifiers
Doi:
10.1016/0035-9203(95)90491-3
ISSN:
00359203
e-ISSN:
18783503
Research Areas
Infectious Diseases
Study Locations
Ethiopia