Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Total cardiovascular risk approach to improve efficiency of cardiovascular prevention in resource constrain settings
Journal of Clinical Epidemiology, Volume 64, No. 12, Year 2011
Notification
URL copied to clipboard!
Description
Objectives: To determine the population distribution of cardiovascular risk in eight low- and middle-income countries and compare the cost of drug treatment based on cardiovascular risk (cardiovascular risk thresholds ≥30%/≥40%) with single risk factor cutoff levels. Study Design and Setting: Using World Health Organization (WHO) and the International Society of Hypertension risk prediction charts, cardiovascular risk was categorized in a cross-sectional study of 8,625 randomly selected people aged 40-80 years (mean age, 54.6 years) from defined geographic regions of Nigeria, Iran, China, Pakistan, Georgia, Nepal, Cuba, and Sri Lanka. Cost estimates for drug therapy were calculated for three countries. Results: A large fraction (90.0-98.9%) of the study population has a 10-year cardiovascular risk <20%. Only 0.2-4.8% are in the high-risk categories (≥30%). Adopting a total risk approach and WHO guidelines recommendations would restrict unnecessary drug treatment and reduce the drug costs significantly. Conclusion: Adopting a total cardiovascular risk approach instead of a single risk factor approach reduces health care expenditure by reducing drug costs. Therefore, limited resources can be more efficiently used to target high-risk people who will benefit the most. This strategy needs to be complemented with population-wide measures to shift the cardiovascular risk distribution of the whole population. © 2011 Elsevier Inc. All rights reserved.
Authors & Co-Authors
Mendis, Shanthi
Unknown Affiliation
Lindholm, Lars Hjalmar J.
Unknown Affiliation
Anderson, Simon George
Unknown Affiliation
Alwan, Ala
Unknown Affiliation
Koju, Rajendra
Unknown Affiliation
Onwubere, Basden J.C.
Unknown Affiliation
Kayani, Azhar Mahmood
Unknown Affiliation
Abeysinghe, Nihal M.R.
Unknown Affiliation
Duneas, Alfredo
Unknown Affiliation
Tabagari, Sergo
Unknown Affiliation
Fan, Wu
Unknown Affiliation
Sarrafzadegan, Nizal S.
Unknown Affiliation
Nordet, Porfirio
Unknown Affiliation
Whitworth, Judith
Unknown Affiliation
Heagerty, Anthony Michael
Unknown Affiliation
Statistics
Citations: 15
Authors: 15
Affiliations: 13
Identifiers
Doi:
10.1016/j.jclinepi.2011.02.001
ISSN:
08954356
e-ISSN:
18785921
Research Areas
Noncommunicable Diseases
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Nigeria