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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
High-risk human papillomavirus types in cytologically normal cervical scrapes from Kenya
Medical Microbiology and Immunology, Volume 180, No. 6, Year 1992
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Description
Seventy-seven women with normal cervical cytology on routine visit to a family planning clinic in Nairobi, Kenya, were analysed for genital human papillomavirus (HPV) types by polymerase chain reaction (PCR). We applied a general primer pair (GP60/GP124) recognising sequences conserved among HPV types 6, 11, 16, 18, 31 and 33. Of the 77 specimens tested 15 (19.5%) proved to be positive for genital HPV. Amplification products were examined for the presence of high-risk HPV types by Slot-blot hybridization. Out of the 15 PCR-positive samples, 4 were positive for HPV 16,3 for HPV 18, while 1 contained both HPV 16 and 33. HPV DNA prevalence in this group of women from a "high-risk" area is similar to that in "low-risk" Swedish women but much lower than in cervical cancer samples from the same region. © 1992 Springer-Verlag.
Authors & Co-Authors
Czeglédy, J.
Hungary, Debrecen
Általános Orvostudományi Kar
Rogo, Khama O.
Kenya, Nairobi
University of Nairobi
Evander, Magnus
Sweden, Umea
Umeå Universitet
Wadell, Göran
Sweden, Umea
Umeå Universitet
Statistics
Citations: 14
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1007/BF00191552
ISSN:
03008584
e-ISSN:
14321831
Research Areas
Cancer
Genetics And Genomics
Health System And Policy
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Study Locations
Kenya
Participants Gender
Female