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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Emergence of Foot-and-Mouth Disease Virus SAT 2 in Egypt During 2012
Transboundary and Emerging Diseases, Volume 59, No. 6, Year 2012
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Description
The epidemiology of foot-and-mouth disease (FMD) in North Africa is complicated by the co-circulation of endemic FMD viruses (FMDV), as well as sporadic incursions of exotic viral strains from the Middle East and Sub-Saharan Africa. This report describes the molecular characterization of SAT 2 FMD viruses that have caused widespread field outbreaks of FMD in Egypt during February and March 2012. Phylogenetic analysis showed that viruses from these outbreaks fell into two distinct lineages within the SAT 2 topotype VII, which were distinct from a contemporary SAT 2 lineage of the same toptype from Libya. These were the first FMD outbreaks due to this serotype in Egypt since 1950 and required the development of a tailored real-time reverse-transcription PCR assay that can be used in the laboratory to distinguish FMD viruses of these lineages from other endemic FMD viruses that might be present in North Africa. These data highlight the ease by which FMDV can cross international boundaries and emphasize the importance of deploying systems to continuously monitor the global epidemiology of this disease. © 2012 Blackwell Verlag GmbH.
Authors & Co-Authors
Ahmed, Hanaa A.
Egypt, Giza
Animal Health Research Institute
Salem, Sayed Ahmed Hassan
Egypt, Giza
Animal Health Research Institute
Habashi, Ahmed R.
Egypt, Giza
Animal Health Research Institute
Arafa, Abdel Satar A.
Egypt, Giza
Animal Health Research Institute
Aggour, Mohamed Galal A.
Egypt, Giza
Animal Health Research Institute
Salem, G. H.
Egypt, Giza
Animal Health Research Institute
Gaber, Amal S.
Egypt, Giza
Animal Health Research Institute
Selem, O.
Egypt, Giza
General Organization for Veterinary Service
Abdelkader, S. H.
Egypt, Giza
General Organization for Veterinary Service
Knowles, Nick James
United Kingdom, Surrey
The Pirbright Institute
Madi, Mikidache
United Kingdom, Surrey
The Pirbright Institute
Valdazo-González, Begoña
United Kingdom, Surrey
The Pirbright Institute
Wadsworth, Jemma
United Kingdom, Surrey
The Pirbright Institute
Hutchings, Geoffrey H.
United Kingdom, Surrey
The Pirbright Institute
Mioulet, Valérie
United Kingdom, Surrey
The Pirbright Institute
Hammond, Jef M.
United Kingdom, Surrey
The Pirbright Institute
King, Donald P.
United Kingdom, Surrey
The Pirbright Institute
Statistics
Citations: 118
Authors: 17
Affiliations: 3
Identifiers
Doi:
10.1111/tbed.12015
ISSN:
18651674
e-ISSN:
18651682
Study Locations
Multi-countries
Egypt
Libya