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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of human immunodeficiency virus seropositivity in head and neck malignancies in sub-Saharan Africa
Acta Oto-Laryngologica, Volume 127, No. 11, Year 2007
Notification
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Description
Conclusion. Salivary gland diseases should be handled with a high index of suspicion. Although an inference could be drawn it is not clear from this study if primary head and neck cancers (HNCs) have a significant association with HIV/AIDS. Objective. HIV/AIDS manifestations and malignancies do occur in the head and neck region. The head and neck surgeon is thus involved in the early identification and management of this group of patients. This study evaluated the prevalence of HIV seropositivity in head and neck malignancies (HNMs) in our centre. Materials and methods. This was a 10 1/2 year (January 1996-June 2006) study of all consecutive cases of histologically confirmed HNMs seen in the ENT department of our centre. Participants had HIV screening by ELISA; those with reactive results had a further confirmatory test (mainly Western blot). Pre-test counselling preceded informed consent of each participant. Seropositive participants had post test counselling. All had surgical biopsy for histology. Results. A total of 521 HNCs (6.6%) were seen in 7941 otolaryngologic consultations within the study period. Males constituted 67.4% and females 32.6% (M:F ratio 2.1:1). Their mean age was 22.1±13.7 years (age range 8-85 years). HNCs were most common in the sixth decade. Ten participants (six males and four females) of the study population were HIV seropositive - a prevalence of 1.9% with 70% being in the 17-45 years age group. Laryngeal cancer (n=163, 31.3%) was the most common HNC. Four (36.4%) of the 11 cases of malignant salivary gland cancers (all parotid) were HIV seropositive. More cases of HIV seropositivity were observed during the HNC peak period of 2004-2006. © 2007 Taylor & Francis.
Authors & Co-Authors
Nwaorgu, Onyekwere George Benjamin
Nigeria, Ibadan
University of Ibadan
Nigeria, Ibadan
University College Hospital, Ibadan
Kokong, Daniel D.
Nigeria, Ibadan
University College Hospital, Ibadan
Onakoya, Paul A.
Nigeria, Ibadan
University of Ibadan
Adoga, Agida Samuel
Nigeria, Jos
University of Jos
Ibekwe, Titus Sunday
Nigeria, Ibadan
University College Hospital, Ibadan
Statistics
Citations: 17
Authors: 5
Affiliations: 3
Identifiers
Doi:
10.1080/00016480701230936
ISSN:
00016489
e-ISSN:
16512553
Research Areas
Cancer
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Participants Gender
Female