Breast cancer in young patient in Morrocco

Objective: The aim of this retrospective study is to determine the epidemiological, clinical, therapeutic aspects and prognostic factors of breast cancer in women through a comparative study of 648 patients treated for breast cancer: 165 patients are at 35 years of age or less (G 1), 286 patients are more than 35 years old and non menopausal (G 2). Patient and method: We have collected, for each group, the epidemioclinical data. Nonmetastatic and operable cancer was treated by surgery (conservative or radical) followed by an adjuvant treatment (chemotherapy, radiotherapy, hormomotherapy) that was indicated according to prognosis factors. Locally advanced forms or metastatic at the moment of diagnosis were treated firstly by chemotherapy. Results: T2N1 forms with lymph node involvement, high grade (SBR II, III) and negative hormonal receptors (HR-) were predominant. There was no difference between the two groups of women concerning risk factors or clinical criterias, except for the mammography that was more sensible in the second group. Conclusion: The breast cancer in our young patient doesn't seem to be different from the older ones either in clinical presentation or evolution. The conclusions of different authors are divergent but they are all for evoluated forms with more defavorable prognosis than in the older women. © 2010.