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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Gangliocytic paraganglioma: A rare case with metastases of all 3 elements to liver and lymph nodes
Annals of Diagnostic Pathology, Volume 15, No. 6, Year 2011
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Description
Gangliocytic paragangliomas are a rare but well-described neuroendocrine tumor with a proclivity for the duodenal area. It is usually a locally infiltrative lesion with a good prognosis. Rare cases that spread to lymph nodes have been documented. A 52-year-old female was found to have a duodenal tumor, enlarged regional lymph nodes, and multiple small nodules in the liver. The duodenal tumor was a classic triphasic gangliocytic paraganglioma. Two regional lymph nodes and one of the nodules in the liver were noted to contain all 3 elements constituting a gangliocytic paraganglioma. This is the second case of gangliocytic paraganglioma with liver spread and is also noteworthy because of the presence of all 3 elements in the metastases. The presence of lymph node and liver metastases should not result in overtreatment as such behavior is not necessarily fraught with a bad clinical outcome. It is probably best to regard such cases as having "uncertain malignant potential" and advocate careful follow-up. © 2011 Elsevier Inc. All rights reserved.
Authors & Co-Authors
Rowsell, Corwyn H.
Canada, Toronto
Sunnybrook Health Sciences Centre
Coburn, Natalie Groce
Canada, Toronto
Sunnybrook Health Sciences Centre
Chetty, Runjan M.
Canada, Toronto
University of Toronto
Statistics
Citations: 27
Authors: 3
Affiliations: 2
Identifiers
Doi:
10.1016/j.anndiagpath.2010.07.009
ISSN:
15328198
Research Areas
Cancer
Study Design
Cohort Study
Participants Gender
Female