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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Serological survey of hepatitis B infection in Tanzania
Public Health, Volume 108, No. 6, Year 1994
Notification
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Description
In 1992, the prevalence of hepatitis B virus (HBV) markers was evaluated in 1004subjects aged one to 76 years living in urban and rural areas in Tanzania. The overall prevalence rates of hepatitis B surface antigen (HBsAg) and of any HBV marker were 4.4% and 37.0%, respectively. No statistically significant difference by sex was found. The HBsAg prevalence among pregnant women was 4.3% (20/463). The proportion of HBsAg positive among HBsAg positive pregnant women was 10% (2/20). The HBsAg age-specific prevalence was 2.1% in the 1-5 year age-group; peak prevalence (12.1%) occurred in the 6-15 year age-group. Markers of HBV infection were 4.1% by age five years; they increased with advancing age (P < 0.01). Subjects residing in urban areas had statistically significant higher HBV exposure than those residing in rural areas (43.9% vs 27.4%, P < 0.01). Subjects belonging to the largest family size (seven or more members) showed increasing risk (OR 2.9; 95% CI = 1.96-4.28) of HBV exposure. Because maternal HBV transmission early in life appears to be of minor impact andchildren are mostly infected later in infancy, HBV vaccination at birth is not indicated, while vaccination of all infants at 2-3 months of age with other paediatric vaccinations is the first priority. © 1994 The Society of Public Health.
Authors & Co-Authors
Pellizzer, Giampietro P.
Italy, Vicenza
Ospedale San Bortolo
Blé, C.
Tanzania, Dodoma
Kondoa District Hospital
Zarnperetti, N.
Tanzania, Dodoma
Kondoa District Hospital
Stroffolini, T.
Italy, Rome
Istituto Superiore Di Sanita
Upunda, G.
Tanzania, Dodoma
Regional Medical Office
Rapicetta, Mariella
Italy, Rome
Istituto Superiore Di Sanita
Chionne, P.
Italy, Rome
Istituto Superiore Di Sanita
Villano, U.
Italy, Rome
Istituto Superiore Di Sanita
Fabris, Paolo
Italy, Vicenza
Ospedale San Bortolo
de Lalla, Fausto
Italy, Vicenza
Ospedale San Bortolo
Statistics
Citations: 28
Authors: 10
Affiliations: 4
Identifiers
Doi:
10.1016/S0033-3506(94)80100-2
ISSN:
00333506
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Tanzania
Participants Gender
Female