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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Bioactive compounds isolated from Aloe ferox: A plant traditionally used for the treatment of sexually transmitted infections in the Eastern Cape, South Africa
Pharmaceutical Biology, Volume 42, No. 8, Year 2004
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Description
Aloe ferox Mill, is one of the plants used for the treatment of sexually transmitted infections (STIs) in the Eastern Cape province of South Africa. Different extracts of the plant were investigated for their antimicrobial constituents. This led to the isolation of three known compounds, namely, 1,8-dihydroxy-3-hydroxymethyl-9,10-anthracenedione (1, aloe-emodin), 1,8-dihydroxy-3-methyl-9,10-anthracenedione (2, chrysophanol), and 10-C-β-D-glucopyranosyl-1,8-dihydroxy-3-hydroxymethyl-9-anthracenone (3, aloin A). The structures of the compounds were determined by chemical and spectroscopic studies. The antibacterial activity of the compounds (1-3) was demonstrated using the microplate dilution method. © 2004 Taylor & Francis Ltd.
Authors & Co-Authors
Kambizi, Learnmore
South Africa, Alice
University of Fort Hare
Sultana, Nasim
Bangladesh, Dhaka
Bangladesh Council of Scientific and Industrial Research Bcsir
Afolayan, Anthony Jide
South Africa, Alice
University of Fort Hare
Statistics
Citations: 59
Authors: 3
Affiliations: 2
Identifiers
Doi:
10.1080/13880200490902581
ISSN:
13880209
Research Areas
Sexual And Reproductive Health
Study Locations
South Africa