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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The impact of HIV on maternal morbidity in the pre-Haart era in Uganda
Journal of Pregnancy, Volume 2012, Article 508657, Year 2012
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Description
Objective. To compare maternal morbidity in HIV-infected and uninfected pregnant women. Methods. Major maternal morbidity (severe febrile illness, illnesses requiring hospital admissions, surgical revisions, or illnesses resulting in death) was measured prospectively in a cohort of HIV-infected and uninfected women followed from 36 weeks of pregnancy to 6 weeks after delivery. Odds ratios of major morbidity and associated factors were examined using logistic regression. Results. Major morbidity was observed in 46/129 (36%) and 104/390 (27%) of the HIV-infected and HIV-uninfected women, respectively, who remained in followup. In the multivariable analysis, major morbidity was independently associated with HIV infection, adjusted odds ratio (AOR) 1.7 (1.1 to 2.7), nulliparity (AOR 2.0 (1.3 to 3.0)), and lack of, or minimal, formal education (AOR 2.1 (1.1 to 3.8)). Conclusions. HIV was associated with a 70 increase in the odds of major maternal morbidity in these Ugandan mothers. © 2012 Harriet Nuwagaba-Biribonwoha et al.
Authors & Co-Authors
Nuwagaba-Biribonwoha, Harriet
United States, New York
Mailman School of Public Health
Mayon-White, Richard T.
United Kingdom, Oxford
University of Oxford
Okong, P.
Uganda, Kampala
St. Francis Hospital Uganda
Brocklehurst, Peter S.
United Kingdom, London
University College London
Carpenter, Lucy J.
United Kingdom, Oxford
University of Oxford
Statistics
Citations: 5
Authors: 5
Affiliations: 4
Identifiers
Doi:
10.1155/2012/508657
ISSN:
20902727
e-ISSN:
20902735
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Cohort Study
Case-Control Study
Study Locations
Uganda
Participants Gender
Female