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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Cost effectiveness of chemotherapy for pulmonary tuberculosis in three sub-Saharan African countries
The Lancet, Volume 338, No. 8778, Year 1991
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Description
The value of programmes to control pulmonary tuberculosis in developing countries remains the subject of debate. We have examined the cost-effectiveness of chemotherapy programmes for the control of pulmonary sputum-smear-positive tuberculosis in Malawi, Mozambique, and Tanzania. Effective cure rates of 86-90% were achieved with short-course chemotherapy and of 60-66% with standard chemotherapy. The average incremental costs per year of life saved were US $1·7-2·1 for short-course chemotherapy with hospital admission, $2·4-3·4 for standard chemotherapy with hospital admission, $0·9-1·1 for ambulatory short-course chemotherapy, and $0·9-1·3 for ambulatory standard chemotherapy. Chemotherapy for smear-positive tuberculosis is thus cheaper than other cost-effective health interventions such as immunisation against measles and oral rehydration therapy. Because the greatest benefit of chemotherapy is reduced transmission of the bacillus, treating HIV-seropositive, tuberculosis smear-positive patients would be only slightly less cost-effective than treating HIV-seronegative, tuberculosis-smear-positive patients. © 1991.
Authors & Co-Authors
Murray, Christopher J.L.
United States, Cambridge
Harvard Center for Population and Development Studies
DeJonghe, E.
Belgium, Brussels
Ministry of Health
Chum, Hamza J.
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare Dar es Salaam
Nyangulu, Daniel S.
Malawi, Lilongwe
Ministry of Health Malawai
Salomao, A.
Mozambique, Maputo
Ministério da Saúde
Styblo, K.
Netherlands, The Hague
Kncv Tuberculosis Foundation
Statistics
Citations: 200
Authors: 6
Affiliations: 6
Identifiers
Doi:
10.1016/0140-6736(91)92600-7
ISSN:
01406736
Research Areas
Cancer
Health System And Policy
Infectious Diseases
Study Locations
Malawi
Mozambique
Tanzania