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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Metadata harmonization–Standards are the key for a better usage of omics data for integrative microbiome analysis
Environmental Microbiomes, Volume 17, No. 1, Article 33, Year 2022
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Description
Background: Tremendous amounts of data generated from microbiome research studies during the last decades require not only standards for sampling and preparation of omics data but also clear concepts of how the metadata is prepared to ensure re-use for integrative and interdisciplinary microbiome analysis. Results: In this Commentary, we present our views on the key issues related to the current system for metadata submission in omics research, and propose the development of a global metadata system. Such a system should be easy to use, clearly structured in a hierarchical way, and should be compatible with all existing microbiome data repositories, following common standards for minimal required information and common ontology. Although minimum metadata requirements are essential for microbiome datasets, the immense technological progress requires a flexible system, which will have to be constantly improved and re-thought. While FAIR principles (Findable, Accessible, Interoperable, and Reusable) are already considered, international legal issues on genetic resource and sequence sharing provided by the Convention on Biological Diversity need more awareness and engagement of the scientific community. Conclusions: The suggested approach for metadata entries would strongly improve retrieving and re-using data as demonstrated in several representative use cases. These integrative analyses, in turn, would further advance the potential of microbiome research for novel scientific discoveries and the development of microbiome-derived products. © 2022, The Author(s).
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC9233336/bin/40793_2022_425_MOESM1_ESM.docx
Authors & Co-Authors
Cernava, Tomislav
Austria, Graz
Technische Universitat Graz
Buscot, François
Germany, Leipzig
Helmholtz Zentrum Für Umweltforschung
Germany, Leipzig
German Centre for Integrative Biodiversity Research Idiv Halle-jena-leipzig
Clavel, Thomas
Germany, Aachen
Uniklinik Rwth Aachen
McHardy, Alice Carolyn
Germany, Braunschweig
Helmholtz Centre for Infection Research Hzi
Germany, Braunschweig
Braunschweiger Zentrum Für Systembiologie
Germany, Hannover
German Center for Infection Research Dzif
Germany, Hannover
Hannover Medical School
Meyer, Folker
Germany, Duisburg
Universität Duisburg-essen
Overmann, Jörg
Germany, Braunschweig
Deutsche Sammlung Von Mikroorganismen Und Zellkulturen Gmbh
Germany, Braunschweig
Technische Universität Braunschweig
Sessitsch, Angela
Austria, Vienna
Austrian Institute of Technology
Schloter, Michael
Germany, Oberschleissheim
Helmholtz Center Munich German Research Center for Environmental Health
Berg, Gabriele
Austria, Graz
Technische Universitat Graz
Germany, Potsdam
Leibniz-institut Für Agrartechnik Und Bioökonomie E.v. Atb
Germany, Potsdam
Universität Potsdam
Bartzanas, Thomas
Unknown Affiliation
Kostić, Tanja
Unknown Affiliation
Champomier Vergès, Marie Christine
Unknown Affiliation
Charles, Trevor C.
Unknown Affiliation
Cotter, Paul D.
Unknown Affiliation
Cowan, Don A.
Unknown Affiliation
D‘Hondt, Kathleen
Unknown Affiliation
Ferrocino, Ilario
Unknown Affiliation
Jansson, Janet K.
Unknown Affiliation
Maguin, Emmanuelle
Unknown Affiliation
Ryan, Matthew J.
Unknown Affiliation
Meisner, Annelein
Unknown Affiliation
Schurr, Ulrich
Unknown Affiliation
Selvin, Joseph A.
Unknown Affiliation
Wagner, Martin
Unknown Affiliation
Wakelin, Steve A.
Unknown Affiliation
de Souza, Rafael Soares Correa
Unknown Affiliation
Dos Ramos, Fernando Jorge
Unknown Affiliation
Lange, Lene
Unknown Affiliation
Smidt, H.
Unknown Affiliation
Statistics
Citations: 9
Authors: 29
Affiliations: 17
Identifiers
Doi:
10.1186/s40793-022-00425-1
ISSN:
25246372
Research Areas
Genetics And Genomics