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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Efficacy of tadalafil in Egyptian and Turkish men with erectile dysfunction
International Journal of Clinical Practice, Volume 60, No. 7, Year 2006
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Description
A randomised, double-blind, parallel, placebo-controlled, 12-week study was carried out to evaluate the efficacy and safety of 20-mg tadalafil taken 'as needed' in a population of men with erectile dysfunction (ED) from Egypt and Turkey. One hundred and thirty-two patients were randomised in this study. Tadalafil was superior to placebo on all three co-primary efficacy end points. The mean change from baseline for the erectile function domain of the International Index of Erectile Function was 9.3 ± 0.8 for the tadalafil group and 2.3 ± 1.6 for the placebo group. Tadalafil-treated patients reported a significantly greater improvement in the mean percentage of successful penetrations (tadalafil: 34.5 ± 4.1; placebo: -4.6 ± 8.1) and successful intercourse attempts (tadalafil: 52.2 ± 3.8; placebo: 16.8 ± 7.8) than placebo-treated patients as measured by the Sexual Encounter Profile. Tadalafil was generally well tolerated with 82% of adverse events being mild in severity. Tadalafil 20-mg taken 'as needed' significantly improved the erectile function in Egyptian and Turkish men with ED. © 2006 Blackwell Publishing Ltd.
Authors & Co-Authors
Saylan, Mete I.
Turkey, Istanbul
Lilly Ilaç Ticaret Limited Sirketi
Turkey, Istanbul
Kisikli Cad
Khalaf, Ismail M.
Egypt, New Damietta
Al-azhar University Hospital
Kadıoğlu, Ateş
Turkey, Istanbul
İstanbul Tıp Fakültesi
Shoair, K. Z.
Egypt, Cairo
Faculty of Medicine
Beheiry, A.
Egypt, Alexandria
Alexandria University Hospitals
Wang, W. C.
United States, Indianapolis
Eli Lilly and Company
Kopernicky, Vladimir
Austria, Vienna
Medical Aesthetic Centre Vienna
Esen, A.
Turkey, Izmir
Dokuz Eylül Üniversitesi
Statistics
Citations: 12
Authors: 8
Affiliations: 9
Identifiers
Doi:
10.1111/j.1742-1241.2006.00993.x
ISSN:
13685031
e-ISSN:
17421241
Research Areas
Disability
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Study Locations
Egypt
Participants Gender
Male