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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Worldwide emergence of multiple clades of enterovirus 68
Journal of General Virology, Volume 93, No. PART 9, Year 2012
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Description
Human enterovirus 68 (EV-D68) is a historically rarely reported virus linked with respiratory disease. In the past 3 years, a large increase in respiratory disease associated with EV-D68 has been reported, with documented outbreaks in North America, Europe and Asia. In several outbreaks, genetic differences were identified among the circulating strains, indicating the presence of multiple clades. In this report, we analyse archived and novel EV-D68 strains from Africa and the USA, obtained from patients with respiratory illness. Phylogenetic analysis of all EV-D68 sequences indicates that, over the past two decades, multiple clades of the virus have emerged and spread rapidly worldwide. All clades appear to be currently circulating and contributing to respiratory disease. © 2012 SGM.
Authors & Co-Authors
Tokarz, Rafal
United States, New York
Mailman School of Public Health
Firth, Cadhla
United States, New York
Mailman School of Public Health
Madhi, Shabir A.
South Africa, Johannesburg
National Institute for Communicable Diseases
South Africa, Johannesburg
University of the Witwatersrand
Howie, Stephen R.C.
Gambia, Banjul
Medical Research Council Laboratories Gambia
Wu, Winfred
United States, New York
New York City Department of Health and Mental Hygiene
Sall, Amadou Alpha
United States, New York
Mailman School of Public Health
Haq, Saddef
United States, New York
Mailman School of Public Health
Briese, Thomas C.
United States, New York
Mailman School of Public Health
Lipkin, W. Ian
United States, New York
Mailman School of Public Health
Statistics
Citations: 201
Authors: 9
Affiliations: 5
Identifiers
Doi:
10.1099/vir.0.043935-0
ISSN:
00221317
e-ISSN:
14652099
Research Areas
Genetics And Genomics