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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The effect of fermented milk on interferon production in malnourished children and in anorexia nervosa patients undergoing nutritional care
European Journal of Clinical Nutrition, Volume 56, Year 2002
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Description
For several years cytokine production has been associated with infections but it was not suspected that some types of food could also induce cytokines, even in a state of non-infection. Lactic bacteria can induce interferon (IFN) production in human healthy subjects, thus, a better protection against infections would be expected. Therefore, we planned to evaluate the effect of two diets including yoghurt or milk on IFN-γ production during nutritional recovery in two different situations of malnutrition: (1) children with diarrhoea; and (2) patients with anorexia nervosa (AN). Both the diet including yoghurt of that including milk seemed to increase IFN-γ production at the end of nutritional recovery in the malnourished children with diarrhoea. The significance of interferon production and the lymphocyte subset increase should be explored to know if a better resistance against pathogens is related to them. Regulation of intestinal absorption and moderate stimulation of interferon production make the yoghurt-based diet a good choice in the nutritional care of children. In the same way, an increase in the IFN-γ production was observed in AN patients consuming yoghurt. This increase of IFN-γ production could be considered a biological marker to detect the effect of probiotics on the immune response, especially in the improvement of a deficient nutritional status. © 2002 Nature Publishing Group.
Authors & Co-Authors
Solis, B.
Spain, Madrid
Inst. de Nutr. y Bromatología
Nova, Esther
Spain, Madrid
Inst. de Nutr. y Bromatología
Gómez, Sonia
Spain, Madrid
Inst. de Nutr. y Bromatología
Samart́in, Sonia
Spain, Madrid
Inst. de Nutr. y Bromatología
Mouane, Nezha
Morocco, Agdal Rabat
Hôpital D'enfants
Lemtouni, Aicha
Morocco, Agdal Rabat
Institut Agronomique et Veterinaire Hassan Ii
Belaoui, H.
Morocco, Agdal Rabat
Laboratoire du Maghreb
Marcos, Ascensioń
Spain, Madrid
Inst. de Nutr. y Bromatología
Statistics
Citations: 31
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.1038/sj.ejcn.1601659
ISSN:
09543007
Research Areas
Food Security
Infectious Diseases
Maternal And Child Health