Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Acute sporadic viral hepatitis in ethiopia: Causes, risk factors, and effects on pregnancy
Clinical Infectious Diseases, Volume 14, No. 4, Year 1992
Notification
URL copied to clipboard!
Description
One hundred and ten consecutive cases of acute sporadic hepatitis among Ethiopian patients were studied to define viral causes, identify risk factors, and analyze demographic and clinical data. IgM antibodies to hepatitis A virus were found in nine patients (8%), and hepatitis B surface antigen and IgM antibodies to hepatitis B core antigen were found in 22 (20%); these findings were considered evidence of acute hepatitis A and hepatitis B, respectively. Sera from the remaining 79 patients were tested for antibodies to hepatitis E virus by a blocking fluorescent antibody test. Thirty-six (33%) of these patients were seropositive, as compared to 4 (7%) of 59 healthy control subjects; for 43 patients (39%), the cause of the acute sporadic hepatitis was unidentified. Twenty-one (19%) of the patients had antibodies to hepatitis C virus, as determined by ELISA. Demographic, biochemical, and clinical data (except in regard to sequelae) were comparable for the different types of infections. The study subjects included 32 pregnant women, 19 (59%) of whom had hepatitis E virus infection; these infections caused death in eight of the women (mostly in the third trimester) and 10 fetal complications. Thus, hepatitis E virus is a common cause of acute sporadic viral hepatitis in Ethiopian patients, and its occurrence during pregnancy is associated with high maternal and fetal morbidity and mortality. © 1992, by The University of Chicago.
Authors & Co-Authors
Tsega, Edemariam
Ethiopia, Addis Ababa
Addis Ababa University
Sweden, Lund
Lunds Universitet
United States, Atlanta
Centers for Disease Control and Prevention
Hansson, Bengt Göran
Ethiopia, Addis Ababa
Addis Ababa University
Sweden, Lund
Lunds Universitet
United States, Atlanta
Centers for Disease Control and Prevention
Krawczyński, Krzysztof Z.
Ethiopia, Addis Ababa
Addis Ababa University
Sweden, Lund
Lunds Universitet
United States, Atlanta
Centers for Disease Control and Prevention
Nordenfelt, Erik
Ethiopia, Addis Ababa
Addis Ababa University
Sweden, Lund
Lunds Universitet
United States, Atlanta
Centers for Disease Control and Prevention
Statistics
Citations: 136
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1093/clinids/14.4.961
ISSN:
10584838
e-ISSN:
15376591
Research Areas
Infectious Diseases
Maternal And Child Health
Sexual And Reproductive Health
Study Locations
Ethiopia
Participants Gender
Female